How Can DNA Replication Be Modeled?

DNA-replication-modelThis hands-on activity can be used to show students how semi-conservative DNA replication occurs. ¬†Students put a DNA molecule together with colored paperclips following the given key and the base pair rule. ¬† Students are then given the steps of replication which involves “unzipping” with helicase and building two new strands using the old strand as a template.

Worksheet also includes discussion questions.


HS-LS3-1 Ask questions to clarify relationships about the role of DNA and chromosomes in coding the instructions for characteristic traits passed from parents to offspring.

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